Sokörpe Skin-Care is Powered by Science
Repair, Revitalize, Maintain and Protect Your Skin Naturally with Sokörpe Skin-Care: The Power of Plants for Healthy, Radiant Skin!
“Only 20-30% Of How We Age Is Determined By Genetics.”
While our genes play a role in determining our physical characteristics, such as skin color and hair type, they have a limited influence on how we age. Many other factors, such as environmental and lifestyle factors, can have a significant impact on the aging process.
Environmental factors, such as sun exposure, pollution, and stress, can damage our skin and accelerate the aging process. Lifestyle factors, such as diet, exercise, and sleep, also play a crucial role in how we age. A healthy lifestyle can help to protect our skin from damage and keep it looking youthful and radiant.
While genetics do play a role in aging, it's essential to understand that we have some control over how we age. By adopting healthy habits and protecting our skin from environmental damage, we can slow down the aging process and keep our skin looking youthful and healthy.
“It’s Mostly Up To You To Determine How You Age”
Skin aging is a complex biological process that is influenced by both internal and external factors. While many people primarily associate skin aging with changes in skin appearance such as wrinkles, fine lines, and age spots, it is important to recognize that skin aging can also have significant effects on skin health, function, and resilience.
Unfortunately, many interventions aimed at addressing skin aging have primarily focused on improving the appearance of the skin, rather than promoting skin health and function. This has led to a proliferation of cosmetic and skincare products and procedures that promise to restore youthful-looking skin, often with little regard for the underlying health and function of the skin.
While improving skin appearance can certainly have psychological benefits and improve self-esteem, it is important to recognize that skin health and function are also important factors in overall well-being. Skin plays a crucial role in protecting the body from external threats such as pathogens, UV radiation, and environmental toxins, and it also helps to regulate body temperature and maintain hydration levels.
Therefore, interventions that prioritize both the aesthetic and functional aspects of skin aging are likely to be the most effective at promoting healthy aging and preventing age-related skin diseases. This may involve a holistic approach that includes lifestyle changes such as a healthy diet and regular exercise, as well as targeted interventions such as the use of natural skincare products that promote skin health and resilience.
What is Cellular senescence?
Cellular senescence is a natural process in which cells stop dividing and enter a state of permanent growth arrest, meaning they can no longer divide and replicate. This process is triggered by a variety of factors, including DNA damage, oxidative stress, and telomere shortening, which occur as a natural part of the aging process.
Cellular senescence is considered to be a protective mechanism that prevents damaged cells from becoming cancerous. However, senescent cells can also contribute to aging and age-related diseases by secreting harmful substances that cause inflammation and damage to surrounding tissues.
Recent research has shown that the accumulation of senescent cells in tissues can contribute to the development of a range of age-related diseases, including arthritis, cardiovascular disease, and neurodegenerative diseases. As a result, there is growing interest in developing therapies that can target senescent cells to slow down or reverse the aging process and improve overall health.
The Hayflick limit deliberates that the average cell will divide around 50 times before reaching a stage known as senescence. As the cell divides, the telomeres on the end of a linear chromosome get shorter. The telomeres will eventually no longer be present on the chromosome. This end stage is the concept that links the deterioration of telomeres to aging.
Senescent cells can induce widespread damage on the skin through several mechanisms. As cells enter senescence, they secrete a range of harmful substances that can contribute to inflammation, damage to surrounding tissues, and impaired tissue repair. In the skin, this can lead to a range of age-related skin concerns, including wrinkles, sagging, and age spots.
One of the primary ways that senescent cells damage the skin is through the secretion of pro-inflammatory cytokines, which trigger an inflammatory response in surrounding tissues. Chronic inflammation is known to accelerate the aging process and can contribute to a range of skin concerns, including wrinkles and loss of elasticity.
Senescent cells also secrete enzymes that degrade the extracellular matrix, a network of proteins that provides support and structure to the skin. This can lead to thinning of the skin and the development of wrinkles and sagging.
In addition, senescent cells can impair the skin's ability to repair itself by reducing the production of growth factors and other proteins necessary for tissue repair. This can lead to impaired wound healing and slower recovery from skin damage.
Overall, the accumulation of senescent cells in the skin can contribute to widespread damage and age-related skin concerns.
The accumulation of senescent cells in the skin is a natural part of the aging process and can contribute to age-related changes in the skin's appearance and function. The more senescent cells you have, the older your skin will behave, meaning it will be more susceptible to damage and show more signs of aging.
Research has shown that the accumulation of senescent cells in the skin can be accelerated by factors such as sun exposure, pollution, and smoking. These factors can cause DNA damage and oxidative stress, triggering the senescence program in skin cells and contributing to the development of age-related skin concerns.
Sokörpe® Laboratories Skin-Care Innovations™ developed skincare therapies that can target senescent cells to slow down or reverse the aging process and improve overall skin health.
Sokörpe’s® skincare formulations, comprised of natural compounds, are capeable of eliminating senescent cells, or intervene to stimulate healthy cells to clear senescent cells from the body.
The more senescent cells you have, the older your skin will behave, meaning it will be more prone to damage and show more signs of aging. It's essential to protect your skin from factors that can accelerate the accumulation of senescent cells, such as sun exposure and smoking, and to adopt a healthy lifestyle to support overall skin health.
One approach to targeting cellular senescence is through the use of senomorphics, which are compounds that can alter the gene expression patterns of senescent cells to make them more similar to young, healthy cells.
Senomorphics are a class of compounds that are designed to alter the gene expression patterns of senescent cells to make them more similar to young, healthy cells.
Senomorphics work by modulating the epigenetic landscape of senescent cells, which is the set of chemical modifications to DNA and associated proteins that can turn genes on or off. By altering the gene expression patterns of senescent cells, senomorphics may be able to rejuvenate these cells and restore their function, potentially leading to improved tissue function and other health benefits.
What Is A Senotherapeutic Molecule?
A senotherapeutic molecule is a type of compound that is designed to target and eliminate senescent cells.
Senotherapeutic molecules work by targeting the specific mechanisms that allow senescent cells to survive and evade the immune system, such as the expression of pro-survival proteins and anti-apoptotic factors. By selectively killing senescent cells, senotherapeutic molecules have the potential to rejuvenate tissues and promote healthy aging.
Palmitoyl Oligopeptide
Palmitoyl oligopeptide, a senotherapeutic molecule compound, does not directly alter the gene expression patterns of senescent cells, but the palmitoyl oligopeptide peptide stimulates collagen production and improves skin elasticity.
Research has suggested that palmitoyl oligopeptide has some senomorphic-like effects. For example, it has been shown to have antioxidant properties and to protect skin cells from oxidative stress, which is a common cause of cellular damage and aging. Additionally, palmitoyl oligopeptide has been shown to have anti-inflammatory effects and to promote wound healing and tissue repair.
Palmitoyl tetrapeptide-7
Palmitoyl tetrapeptide-7 works by reducing the production of interleukin-6 (IL-6), a pro-inflammatory cytokine that is often elevated in aging and age-related diseases. By reducing the production of IL-6, palmitoyl tetrapeptide-7 may be able to improve tissue function and reduce inflammation.
While palmitoyl tetrapeptide-7 does not directly target senescent cells or alter gene expression patterns, it may have some senomorphic-like effects by reducing inflammation and improving tissue function.
Palmitoyl Tripeptide-5
Palmitoyl tripeptide-5, a senotherapeutic molecule compound, works by activating the TGF-beta pathway, which is involved in cellular proliferation and differentiation, tissue repair, and immune regulation. By activating this pathway, palmitoyl tripeptide-5 is be able to improve tissue function and promote tissue repair.
While palmitoyl tripeptide-5 does not directly target senescent cells or alter gene expression patterns, it may have some senomorphic-like effects by promoting tissue repair and improving tissue function.
Plankton
Plankton is a diverse group of organisms that includes bacteria, algae, and protists, among others. Some species of plankton have senomorphic-like effects, such as promoting tissue repair or reducing inflammation.
Some species of plankton, such as certain types of microalgae, have been studied for their potential health benefits and anti-aging properties. For example, some microalgae have been shown to have antioxidant properties, which can help to protect cells from oxidative stress and damage. Additionally, some species of plankton have been studied for their potential ability to stimulate collagen production and improve skin elasticity.
Wakame Bioferment
Wakame bioferment is a natural extract derived from the wakame seaweed and improves skin texture and reduces the appearance of wrinkles and fine lines.
Wakame bioferment contains a variety of nutrients and bioactive compounds, including vitamins, minerals, and antioxidants, that help to promote skin health and reduce the signs of aging. For example, it has been shown to have anti-inflammatory and antioxidant properties, which can help to protect skin cells from damage and reduce inflammation.
While wakame bioferment does not directly target senescent cells or alter gene expression patterns, it may have some senomorphic-like effects by improving tissue function and reducing inflammation.
Beta-Carotene
Beta-carotene is a naturally occurring pigment found in many fruits and vegetables, such as carrots, sweet potatoes, and spinach, among others. It is a precursor to vitamin A and is converted to vitamin A in the body.
Beta-carotene is known for its antioxidant properties and has been shown to help protect cells from damage caused by free radicals, which are molecules that can damage cells and contribute to aging and age-related diseases.
Adenosine
Adenosine, a senotherapeutic molecule compound, does not directly alter the gene expression patterns of senescent cells, however, adenosine is a naturally occurring compound that is involved in a wide range of cellular processes, including energy metabolism, DNA synthesis and repair, and signal transduction.
Recent research has suggested that adenosine may have some senomorphic-like effects. For example, adenosine has been shown to have anti-inflammatory effects and to promote tissue repair and regeneration. Additionally, adenosine has been shown to activate certain signaling pathways that are known to be involved in cellular rejuvenation and anti-aging.
The Synergistic Blend
In the field of bioscience, a synergistic blend refers to the interaction of two or more substances to produce a combined effect that is greater than the sum of their individual effects.
The aforementioned ingredients and compounds have been carefully combined by Sokörpe® Laboratories Skin-Care Innovations™ into a synergistic blend taking into account the complex and interconnected nature of the skin. Different natural ingredients can have complementary effects on the skin, and their combination can help to achieve a more balanced and effective treatment.
The use of a synergistic blend can help to achieve a more comprehensive and effective treatment that addresses the underlying causes of skin issues, rather than just their symptoms.
By Alexander Brosda, CEO Sokörpe Laboratories
